Gif Central boasts hundreds of funny animated gifs. Only the best of the best make it onto this site, with most of them having an accompanying source. No tumblr-esque one-second-long disappointments. No obscure titles or descriptions.
This is an animated gif of Dean Winchester / Jensen Ackles crying. The tear running down his face makes for a great reaction whenever somebody says mean or dispirited. Or, if you simply hear news that you dislike.